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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPV5 All Species: 18.48
Human Site: S689 Identified Species: 36.97
UniProt: Q9NQA5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQA5 NP_062815.2 729 82551 S689 A L P T S S L S R T A S Q S S
Chimpanzee Pan troglodytes XP_519444 729 82502 S689 A L P T S S L S R T A S Q S S
Rhesus Macaque Macaca mulatta XP_001089988 729 82599 S689 A L P N S S L S R T T S Q S S
Dog Lupus familis XP_539860 808 91760 S767 A P P T P S L S R T T S H S S
Cat Felis silvestris
Mouse Mus musculus P69744 723 82199 S682 V L Q T P P L S R T T S L S S
Rat Rattus norvegicus Q9JIP0 723 82435 S682 V L Q T P P L S R T T S L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518104 356 39437 L317 A V R L V G E L L T V V G A V
Chicken Gallus gallus XP_416530 724 82934 Y676 E V D R N I L Y K K D L S I P
Frog Xenopus laevis NP_001082336 674 75844 R634 S Q E L E G S R A P M A Q R R
Zebra Danio Brachydanio rerio NP_001001849 707 80910 E666 K P S K S D G E Q S I T E S N
Tiger Blowfish Takifugu rubipres NP_001027938 719 81679 K680 E P T Q F G L K T T E S L N R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6AWW5 524 56905 G485 L I M V S T L G T M C Y W V I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.8 78.4 N.A. 80.6 79.9 N.A. 34.7 68.7 50.8 46.9 51.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98 83.2 N.A. 88.8 89 N.A. 40.5 82.9 66.6 68.5 69.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 60 60 N.A. 13.3 6.6 6.6 13.3 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 73.3 N.A. 60 60 N.A. 26.6 26.6 20 46.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 0 0 0 0 0 0 9 0 17 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 0 0 9 0 0 0 0 % D
% Glu: 17 0 9 0 9 0 9 9 0 0 9 0 9 0 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 25 9 9 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 0 0 9 0 0 0 0 9 0 0 9 9 % I
% Lys: 9 0 0 9 0 0 0 9 9 9 0 0 0 0 0 % K
% Leu: 9 42 0 17 0 0 75 9 9 0 0 9 25 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 9 9 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 0 0 0 0 9 9 % N
% Pro: 0 25 34 0 25 17 0 0 0 9 0 0 0 0 9 % P
% Gln: 0 9 17 9 0 0 0 0 9 0 0 0 34 0 0 % Q
% Arg: 0 0 9 9 0 0 0 9 50 0 0 0 0 9 17 % R
% Ser: 9 0 9 0 42 34 9 50 0 9 0 59 9 59 50 % S
% Thr: 0 0 9 42 0 9 0 0 17 67 34 9 0 0 0 % T
% Val: 17 17 0 9 9 0 0 0 0 0 9 9 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _